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number of CCs smoked per day) was used to calculate adjusted odds ratios (AORs) of experiencing at least one type of adverse event according to use patterns, comparing exclusive CC smokers with dual users of CCs plus ECs and/or HTPs

Food and Drug Administration (FDA) and Developed by 22nd Century Group, Inc., The tobacco was developed over 10 years of research and through more than 50 government-funded, independent clinical trials by or for esteemed public health institutions and universities, including: the FDA

This information was adapted from NHS Choices